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In this study a macrolide antiparasitic agent, could overcome the resistance of cancer cells to the therapeutic drugs. Composition: Acyclovir (400mg) Usage/Application: Herpes Simplex, Virus Infections, Chickenpox, Herpes labialis, Shingles Genital Zovirax 400 Tab. Composition: Acyclovir (400mg) Usage/Application: Herpes Simplex, Virus Infections, Chickenpox, Herpes labialis, Shingles Genital Zovirax 400 Tab. Other mechanisms of resistance include altered substrate specificity of thymidine kinase and reduced sensitivity of viral DNA polymerase. Other mechanisms of resistance include altered substrate specificity of thymidine kinase and reduced sensitivity of viral DNA polymerase. Airway insertion; airway management; dysrhythmia management sinus tachycardia treat the underlying arch of the esophagus). Airway insertion; airway management; dysrhythmia management sinus tachycardia treat the underlying arch of the esophagus). Gagging and anorexia have actually likewise been stated. 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